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Webinar

Improving CAR-T immunotherapy for lymphoma by fine-tuning avidity

Marco Ruella, MD
Assistant Professor of Medicine and Scientific Director of the Lymphoma Program
0:00

Abstract

Commercial CAR-T therapies still suffer from severe limitations, as majority of patients fail to achieve complete response and ultimately relapse.

Watch this Webinar to discover Prof. Marco Ruella’s team have adopted a novel CAR-T avidity screening method to improve safety and exhaustion profile, leading to 100% clinical response in a phase I trial.

What you'll learn

  • How an innovative CAR binder leads to enhanced clinical response compared to currently available commercial CAR.
  • How tuning the fine balance between T cell engagement and exhaustion in CAR T cells leads to a more durable anti-tumor response and superior clinical outcome.
  • The innovative strategy used to reduce Activation-Induced Cell Death (AICD) in CAR T cells, a key challenge in providing durable and complete response for patients.

Relevant resources

Learn as much as you can by reading up on our application notes or marathoning our webinars.

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