Imagine measuring the combined strength of cell-cell / cell-protein binding, generating direct, physiologically relevant measurements of binding in its full, dynamic complexity. To support progress in immunotherapy, we need to measure binding the way it happens—in real life, in real cells. This is Cell Avidity.
What if you could measure molecular properties and interactions while simultaneously revealing the processes in real-time? A technology that unravels the crucial and dynamic interactions taking place at the molecular level and gives you direct proof of the mechanisms involved. Our Dynamic Single-Molecule technology provides you with all of that, enabling the understanding of the root of disease development at the molecular level and accelerate therapeutic breakthroughs.

"I think applications like the C-Trap will become more mainstream in terms of understanding DNA transaction-based reactions."

"Fine-tuning the cell avidity of anti-CAIX CAR T cells [enabled us to] mitigate on-target, off-tumor toxicity, [...] ensuring only CAIX-high tumor cells are killed."

"[Cell] Avidity measurement[s] will be an essential tool to screen the constructs and the products that you want to bring to the clinic."

"Interestingly, of the pre-clinical assays we used to compare CAR constructs, only [Cell] Avidity correlated with in vivo results."

"The C-Trap has allowed us to ask those questions we couldn't probe before. We go down to the C-Trap room and it works first-time."