Publications
Dynamic Single-Molecule
Thank you! Your submission has been received!
Oops! Something went wrong while submitting the form.
Thank you! Your submission has been received!
Oops! Something went wrong while submitting the form.
Single-Molecule Force Spectroscopy Reveals a High-Force Requirement for Dissociation of Integrin Transmembrane Domains
Hadawi, M. et al.
2026
Biophysical Journal
This is some text inside of a div block.
Mechanism underlying the high regulatory performance of the doxycycline riboswitch G12
Hoetzel, J. et al.
2026
Nature Communications
This is some text inside of a div block.
Large intra-chromosome heterogeneity leads to emergent nonlinear mechanics
van der Smagt, C. et al.
2026
Nature Physics
This is some text inside of a div block.
From single DNA molecule to nanoparticle formation: mechanistic basis for monocationic aromatic drug-induced DNA frameworks
Villamizar-Sarmiento, M.G. et al.
2026
Journal of Nanobiotechnology
This is some text inside of a div block.
Nanovesicles With Mechanically Induced Adjuvanticity for Robust Melanoma Vaccination Toward Tumor-Associated Macrophages
Luo, B. et al.
2026
Advanced Science
This is some text inside of a div block.
Small Molecule Activators of Protein Phosphatase 2A Exert Global Stabilizing Effects on the Scaffold PR65
Naqvi, M. M. et al.
2026
JACS
This is some text inside of a div block.
Dual and opposing roles of the EXD2 exonuclease in the resolution of RNA–DNA hybrids
Hu, M. et al.
2026
Nucleic Acids Research
This is some text inside of a div block.
Dpb11 facilitates the colocalization of Mec1-Ddc2 with its activators on gapped DNA
Beckwitt, E. C. et al.
2026
Cell Reports
This is some text inside of a div block.
Cellular replisomes are powered by flex-fuel motors for unwinding DNA
Rashid, F.
2026
Nature Communications
This is some text inside of a div block.
APE1 binds and processes abasic sites present in i-motif DNA and cooperates with PCBP1 in maintenance of telomeric stability
Bellina, A. et al.
2026
Nucleic Acids Research
This is some text inside of a div block.
Molecular tension indicators reveal unexpectedly complex regulation of tension in live mouse organs
Fujiwara, K. et al.
2026
Communications Biology
This is some text inside of a div block.
The eukaryotic homology search complex distorts donor DNA structure to probe for homology
Woodhouse, M. V.et al.
2026
Genes & Development
This is some text inside of a div block.
VGLL4-driven TEAD4 multimerization orchestrates DNA binding and YAP recruitment
Ren, Z. et al.
2026
Nature Communications
This is some text inside of a div block.
Membrane-Coated Microsphere Functionalization with Polypeptides
Christopher J. et al.
2026
Biomacromolecules
This is some text inside of a div block.
HSV-1 origin binding protein UL9 forms intermolecular DNA tethers and intramolecular DNA loops
Meier, A.F. et al.
2026
Nature Communications
This is some text inside of a div block.
Concurrent positional dynamics and activity mapping of DNA-binding proteins
Xu, L. et al.
2026
Nature Protocols
This is some text inside of a div block.
RPA–ssDNA co-phase separation facilitates RAD51 enrichment during homologous recombination
Li, Y. et al.
2026
Nucleic Acids Research
This is some text inside of a div block.
The DdmDE defense system eradicates plasmids by target-centered bidirectional ssDNA loop extrusion and site-specific cleavage
Yang, H. et al.
2026
Molecular Cell
This is some text inside of a div block.
The human RAD52 complex undergoes phase separation and facilitates bundling and end-to-end tethering of RAD51 presynaptic filaments
Alshareedah, I. et al.
2026
Nucleic Acids Research
This is some text inside of a div block.
Vimentin networks at high strains
Zafari, S. et al.
2026
Physical Review Research
This is some text inside of a div block.
A dynamic search mechanism enables APE1 to identify AP-sites in DNA
DeHart, K. M. et al.
2026
Nucleic Acids Research
This is some text inside of a div block.
Decoupling phase separation and fibrillization preserves activity of biomolecular condensates
Mahendran, T. S. et al.
2026
Nature Communications
This is some text inside of a div block.
Regulation of Pfh1 helicase activity by nucleic acid interactions and mitochondrial SSB
Ortiz-Rodríguez, M. et al.
2026
PNAS
This is some text inside of a div block.
Condensin I but not Condensin II is crucial for mitotic chromosome mechanics
Nielsen, C. F. et al.
2026
Nature Communications
This is some text inside of a div block.
Direct observation of ATP-driven ubiquitin chain handling by Cdc48
Choudhary, D. et al.
2026
Nature Communications
This is some text inside of a div block.
OT-Curtains: an approach for studying protein interactions with DNA ends using optical tweezers and confocal fluorescence microscopy
De Bragança, S. et al.
2026
Nucleic Acids Research
This is some text inside of a div block.
Cryo–electron microscopy visualization of RAD51 filament assembly and end-capping by XRCC3-RAD51C-RAD51D-XRCC2
Greenhough, L. A. et al.
2025
Science
This is some text inside of a div block.
Influence of Substrate on Supported Lipid Bilayers: Membrane Adhesion, Stretching, Pores, and Remodeling
Lira, R. B. et al.
2026
Langmuir
This is some text inside of a div block.
Measuring bridging forces in protein–DNA condensates
Ahlawat, V. et al.
2026
PNAS
This is some text inside of a div block.
Single Molecule Force Measurements Reveal Energy Stabilization of Theophylline Aptamer RNA Switch Required for Gene Control
Liu, F. A. et al.
2026
ACS Physical Chemistry Au
This is some text inside of a div block.
Type III Collagen Promotes a Pro‐Fibrotic Microenvironment for In Vitro Tendon Healing Microphysiological Systems
Zhang, V. Z. et al.
2026
Journal of Orthopaedic Research
This is some text inside of a div block.
Calmodulin assists during co-translational folding of the KV7.2 channel calcium responsive domain
Muguruza-Montero, A. et al.
2026
Protein Science
This is some text inside of a div block.
MYC modulates TOP2A diffusion to promote substrate detection and activity
Cameron, D. P. et al.
2026
Nature Communications
This is some text inside of a div block.
Structural basis of supercoiling-induced CRISPR–Cas9 off-target activity
Smith, Q.M. et al.
2026
Nature
This is some text inside of a div block.
Molecular determinants of Smc5/6 association with DNA junctions
Chang, J. T. et al.
2026
Nature Communications
This is some text inside of a div block.
NAC promotes co-translational protein folding at the ribosomal tunnel exit
Santos, J. et al.
2026
Molecular Cell
This is some text inside of a div block.
Adaptor-mediated recruitment of three dyneins to dynactin enhances force generation
Rao, L. et al.
2026
Nature Cell Biology
This is some text inside of a div block.
Tuning the sensitivity of mechanosensory receptors through histidine scanning
Wang, Y. et al.
2026
Cell
This is some text inside of a div block.
Quantifying the effect of magnesium ions on nucleosome stability in chromatin fibers
Daris, L. J. et al.
2026
Biophysical Journal
This is some text inside of a div block.
HOP2–MND1 chaperones a diffusing DMC1–ssDNA complex to survey dsDNA for homology recognition during meiotic recombination
Cheng, B. et al.
2026
PNAS
This is some text inside of a div block.
Optical tweezers force–fluorescence spectroscopy in investigations of DNA replication
Liu, Z. et al.
2026
Advances in Physics: X
This is some text inside of a div block.
Nucleosome spacing regulates linker methylation by DNMT3A2/3B3
Xie, X. et al.
2026
Molecular Cell
This is some text inside of a div block.
Mechanistic basis for relaxation of DNA supercoils by human topoisomerase IIIα–RMI1–RMI2
Spakman, D. et al.
2026
PNAS
This is some text inside of a div block.
A non-catalytic role for RFC in PCNA-mediated processive DNA synthesis
Chua, G. N. et al.
2026
Cell
This is some text inside of a div block.
Type I-Fv and engineered type IV-A1 CRISPR–Cas effectors facilitate genome reduction in Escherichia coli
Klein, N. et al.
2025
Nucleic Acids Research
This is some text inside of a div block.
Nucleosome unwrapping and PARP1 allostery drive affinities for chromatin and DNA breaks
Schaich, M. A. et al.
2025
Nature Communications
This is some text inside of a div block.
Mechanisms of HSV-1 helicase-primase inhibition and replication fork complex assembly
Yu, Z. et al.
2025
Cell
This is some text inside of a div block.
The zinc finger of DNA ligase 3α binds to nucleosomes via an arginine anchor
Nagpal, A. et al.
2025
Nature Communications
This is some text inside of a div block.
H4K16 acylations destabilize chromatin architecture and facilitate transcriptional response during metabolic perturbations
Nitsch, S. et al.
2025
Molecular Cell
This is some text inside of a div block.
Structural Studies on the M. tuberculosis Nucleoid-associated-Protein, NapA, Indicates DNA Bridging Mechanism
Schumacher, M. A. et al.
2025
J. Molecular Biology
This is some text inside of a div block.
Kinesin-1 autoinhibition tunes cargo transport by motor ensembles
Bensel, B. M. et al.
2025
Biophysical Journal
This is some text inside of a div block.
Dynamics of ultrafine silver implanted DNA nanowire formation
Ma, Q. et al.
2025
Nanoscale
This is some text inside of a div block.
One-pot dual protein labeling for simultaneous mechanical and fluorescent readouts in optical tweezers
Silbermann, L. M. et al.
2025
Protein Science
This is some text inside of a div block.
Coexistence of G-Quadruplex and i-Motif Within a DNA Duplex is Tolerated by a PCBP2-Assisted Replisome
Bao, Y. et al.
2025
Angewandte Chemie
This is some text inside of a div block.
Functional interplay between condensin I and topoisomerase IIα in single-molecule DNA compaction
Tsubota, Y. et al.
2025
Nature Communications
This is some text inside of a div block.
A Versatile GPMV-Imaging Platform for Quantitative Analysis of Receptor Binding and Membrane Fusion
Yosibash, I. et al.
2025
Biophysical Journal
This is some text inside of a div block.
Elongator is a microtubule polymerase selective for polyglutamylated tubulin
Planelles-Herrero, V.J. et al.
2025
The EMBO Journal
This is some text inside of a div block.
SON-dependent nuclear speckle rehabilitation alleviates proteinopathies
Dion, W. et al.
2025
Nature Communications
This is some text inside of a div block.
Programmable Protein-DNA Composite Nanostructures:from Nanostructure Construction to Protein-InducedMicro-Scale Material Self-Assembly and Functionalization
Zhou, W. et al.
2025
Small
This is some text inside of a div block.
Co-translational ribosome pairing enables native assembly of misfolding-prone subunits
Wruck, F. et al.
2025
Nature Communications
This is some text inside of a div block.
DNA polymerase actively and sequentially displaces single-stranded DNA-binding proteins
Xu, L. et al.
2025
Nature Communications
This is some text inside of a div block.
Metabolically intact nuclei are fluidized by the activity of the chromatin remodeling motor BRG1
Byfield, F. J. et al.
2024
Biophysical Journal
This is some text inside of a div block.
Controlling interfacial protein adsorption, desorption and aggregation in biomolecular condensates
Visser, B.S. et al.
2025
Nature Communications
This is some text inside of a div block.
Multiscale structure of chromatin condensates explains phase separation and material properties
Zhou, H. et al.
2025
Science
This is some text inside of a div block.
Kinetic control of mammalian transcription elongation
Wang, Y. et al.
2025
Nature Structural & Molecular Biology
This is some text inside of a div block.
Roles of histone chaperone Nap1 and histone acetylation in regulating phase-separation of nucleosome arrays
Gao, J. et al.
2025
Nature Communications
This is some text inside of a div block.
Structure and DNA-bridging activity of the essential Rec114–Mei4 trimer interface
Liu, K. et al.
2023
Cold Spring Harbor Laboratory Press
This is some text inside of a div block.
Insights into new mechanosensitive behaviors of G protein-coupled receptors
Shetty, A. J. et al.
2025
Journal of Molecular Endocrinology
This is some text inside of a div block.
Nanoscale domains govern local diffusion and ageing within fused-in-sarcoma condensates
Gao, G. et al.
2025
Nature Nanotechnology
This is some text inside of a div block.
Protocol to quantify mechanical properties of cells using optical tweezers
Rodenburg, W. S. et al.
2025
STAR Protocols
This is some text inside of a div block.
Cryo-EM reveals open and closed Asgard chromatin assemblies
Ranawat, H. M. et al.
2025
Molecular Cell
This is some text inside of a div block.
Revealing Mechanopathology Induced by Dengue NS1 Using Organ Chips and Single-Cell Force Spectroscopy
Tang, H. et al.
2025
ACS Biomaterials Science & Engineering
This is some text inside of a div block.
Cryo–electron microscopy visualization of RAD51 filament assembly and end-capping by XRCC3-RAD51C-RAD51D- XRCC2
Greenhough, L. A. et al.
2025
Science
This is some text inside of a div block.
Coupling of Spectrin Repeat Modules for the Assembly of Nanorods and Presentation of Protein Domains
Coupling of Spectrin Repeat Modules for the Assembly of Nanorods and Presentation of Protein Domains
Mezgec, K. et al.
2025
ACS Nano
This is some text inside of a div block.
Phase-separated NDF−FACT condensates facilitate transcription elongation on chromatin
Li, Z. et al.
2025
Nature Cell Biology
This is some text inside of a div block.
Programmable Protein-DNA Composite Nanostructures: from Nanostructure Construction to Protein-Induced Micro-Scale Material Self-Assembly and Functionalization
Zhou, W. et al.
2025
Small
This is some text inside of a div block.
Sequence-dependent folding of monolayered DNA origami domains
Gambietz, S. et al.
2023
Nanoscale
This is some text inside of a div block.
FUS Oncofusion Protein Condensates Recruit mSWI/SNF Chromatin Remodeler via Heterotypic Interactions Between Prion-like Domains
Davis, R. B. et al.
2021
Protein Science
This is some text inside of a div block.
Single-stranded nucleic acid binding and coacervation by linker histone H1
Leicher, R. et al.
2022
Nature Structural & Molecular Biology
This is some text inside of a div block.
Chromatin sequesters pioneer transcription factor Sox2 from exerting force on DNA
Nguyen, T. et al.
2022
Nature Communications
This is some text inside of a div block.
The membrane-actin linker ezrin acts as a sliding anchor
Korkmazhan, E. et al.
2022
Science Advances
This is some text inside of a div block.
Keratin filament mechanics and energy dissipation are determined by metal-like plasticity
Lorenz, C. et al.
2023
Matter
This is some text inside of a div block.
Ion-mediated condensation controls the mechanics of mitotic chromosomes
Witt, H. et al.
2024
Nature Materials
This is some text inside of a div block.
Localized Plasmonic Heating for Single-Molecule DNA Rupture Measurements in Optical Tweezers
Kabtiyal, P. et al.
2024
Nanoscale
This is some text inside of a div block.
Phase separation-competent FBL promotes early pre-rRNA processing and translation in acute myeloid leukaemia
Yang, L. et al.
2024
Nature Cell Biology
This is some text inside of a div block.
Mapping fast DNA polymerase exchange during replication
Xu, L. et al.
2024
Nature Communications
This is some text inside of a div block.
Exerting pulling forces in fluids by directional disassembly of microcrystalline fibres
Pantaleone, L. C. et al.
2024
Nature Nanotechnology
This is some text inside of a div block.
In Situ Nucleosome Assembly for Single-Molecule Correlative Force and Fluorescence Microscopy
Ng, H. et al.
2024
JoVE
This is some text inside of a div block.
Amino acid-dependent phase equilibrium and material properties of tetrapeptide condensates
Zhang, Y. et al.
2024
Cell Reports Physical Science
This is some text inside of a div block.
Dynamic phosphorylation of FOXA1 by Aurora B guides post-mitotic gene reactivation
Zhang, T. et al.
2024
Cell Reports
This is some text inside of a div block.
Structural basis of antimicrobial membrane coat assembly by human GBP1
Kuhm, T. et al.
2024
Nature Structural & Molecular Biology
This is some text inside of a div block.
CRISPR-AsCas12f1 couples out-of-protospacer DNA unwinding with exonuclease activity in the sequential target cleavage
Song, X. et al.
2024
Nucleic Acids Research
This is some text inside of a div block.
Force-transducing molecular ensembles at growing microtubule tips control mitotic spindle size
Chu, L. Y. et al.
2024
Nature Communications
This is some text inside of a div block.
L1-ORF1p nucleoprotein can rapidly assume distinct conformations and simultaneously bind more than one nucleic acid
Cashen, B. A. et al.
2024
Nucleic Acids Research
This is some text inside of a div block.
Autoregressive HMM resolves biomolecular transitions from passive optical tweezer force measurements
Autoregressive HMM resolves biomolecular transitions from passive optical tweezer force measurements
Dawes, B. A. et al.
2024
Biophysical Journal
This is some text inside of a div block.
Increased perfluorooctanoic acid accumulation facilitates the migration and invasion of lung cancer cells via remodeling cell mechanics
Mei, J. et al.
2024
PNAS
This is some text inside of a div block.
The recombination efficiency of the bacterial integron depends on the mechanical stability of the synaptic complex
Vorobevskaia, E. et al.
2024
Science Advances
This is some text inside of a div block.
Intracellular pressure controls the propagation of tension in crumpled cell membranes
Dharan, R. et al.
2025
Nature Communications
This is some text inside of a div block.
Binuclear ruthenium complex linker length tunes DNA threading intercalation kinetics
Almaqwashi, A. A. et al.
2025
Biophysical Journal
This is some text inside of a div block.
KorB switching from DNA-sliding clamp to repressor mediates long-range gene silencing in a multi-drug resistance plasmid
McLean, T. C. et al.
2025
Nature Microbiology
This is some text inside of a div block.
There’s nothing here!
Try using a different combination of search criteria