Publications
Dynamic Single-Molecule
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Programmable Protein-DNA Composite Nanostructures: from Nanostructure Construction to Protein-Induced Micro-Scale Material Self-Assembly and Functionalization
Zhou, W. et al.
2025
Small
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Sequence-dependent folding of monolayered DNA origami domains
Gambietz, S. et al.
2023
Nanoscale
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FUS Oncofusion Protein Condensates Recruit mSWI/SNF Chromatin Remodeler via Heterotypic Interactions Between Prion-like Domains
Davis, R. B. et al.
2021
Protein Science
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Single-stranded nucleic acid binding and coacervation by linker histone H1
Leicher, R. et al.
2022
Nature Structural & Molecular Biology
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Chromatin sequesters pioneer transcription factor Sox2 from exerting force on DNA
Nguyen, T. et al.
2022
Nature Communications
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The membrane-actin linker ezrin acts as a sliding anchor
Korkmazhan, E. et al.
2022
Science Advances
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Keratin filament mechanics and energy dissipation are determined by metal-like plasticity
Lorenz, C. et al.
2023
Matter
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Ion-mediated condensation controls the mechanics of mitotic chromosomes
Witt, H. et al.
2024
Nature Materials
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Localized Plasmonic Heating for Single-Molecule DNA Rupture Measurements in Optical Tweezers
Kabtiyal, P. et al.
2024
Nanoscale
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Phase separation-competent FBL promotes early pre-rRNA processing and translation in acute myeloid leukaemia
Yang, L. et al.
2024
Nature Cell Biology
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Mapping fast DNA polymerase exchange during replication
Xu, L. et al.
2024
Nature Communications
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Exerting pulling forces in fluids by directional disassembly of microcrystalline fibres
Pantaleone, L. C. et al.
2024
Nature Nanotechnology
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In Situ Nucleosome Assembly for Single-Molecule Correlative Force and Fluorescence Microscopy
Ng, H. et al.
2024
JoVE
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Amino acid-dependent phase equilibrium and material properties of tetrapeptide condensates
Zhang, Y. et al.
2024
Cell Reports Physical Science
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Dynamic phosphorylation of FOXA1 by Aurora B guides post-mitotic gene reactivation
Zhang, T. et al.
2024
Cell Reports
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Structural basis of antimicrobial membrane coat assembly by human GBP1
Kuhm, T. et al.
2024
Nature Structural & Molecular Biology
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CRISPR-AsCas12f1 couples out-of-protospacer DNA unwinding with exonuclease activity in the sequential target cleavage
Song, X. et al.
2024
Nucleic Acids Research
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Force-transducing molecular ensembles at growing microtubule tips control mitotic spindle size
Chu, L. Y. et al.
2024
Nature Communications
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L1-ORF1p nucleoprotein can rapidly assume distinct conformations and simultaneously bind more than one nucleic acid
Cashen, B. A. et al.
2024
Nucleic Acids Research
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Autoregressive HMM resolves biomolecular transitions from passive optical tweezer force measurements
Autoregressive HMM resolves biomolecular transitions from passive optical tweezer force measurements
Dawes, B. A. et al.
2024
Biophysical Journal
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Increased perfluorooctanoic acid accumulation facilitates the migration and invasion of lung cancer cells via remodeling cell mechanics
Mei, J. et al.
2024
PNAS
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The recombination efficiency of the bacterial integron depends on the mechanical stability of the synaptic complex
Vorobevskaia, E. et al.
2024
Science Advances
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Intracellular pressure controls the propagation of tension in crumpled cell membranes
Dharan, R. et al.
2025
Nature Communications
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Binuclear ruthenium complex linker length tunes DNA threading intercalation kinetics
Almaqwashi, A. A. et al.
2025
Biophysical Journal
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KorB switching from DNA-sliding clamp to repressor mediates long-range gene silencing in a multi-drug resistance plasmid
McLean, T. C. et al.
2025
Nature Microbiology
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Cell-associated galectin 9 interacts with cytotoxic T cells confers resistance to tumor killing in nasopharyngeal carcinoma through autophagy activation
Kam, N. W. et al.
2025
Cellular & Molecular Immunology
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Single-Molecule Insight Into α-Synuclein Fibril Structureand Mechanics Modulated by Chemical Compounds
Li, X. et al.
2025
Advanced Science
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Robust quantification of cellular mechanics using optical tweezers
Rodenburg, W. S. et al.
2025
Biophysical Reports
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Bridging Mechanical Properties with Atomic Structures of Polymorphic _-Synuclein Fibrils by Single-Molecule Analysis and Molecular Dynamics Simulations
Bi, L. et al.
2025
Aggregate
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Roquin exhibits opposing effects on RNA stem- _ loop stability through its two ROQ domain binding sites
Tants, J. N. et al.
2025
PNAS
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Measuring interactions between Pickering emulsion droplets coated with caseinÐchitosan complex using optical tweezers
Ma, Q. et al.
2025
RSC Advances
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The YoaA-_ helicase modulates the dynamics of single-stranded DNA binding protein on DNA
Weeks-Pollenz, S. J. et al.
2025
Nature Communications
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Proteome-wide determinants of co-translational chaperone binding in bacteria
Galmozzi, C. V. et al.
2025
Nature Communications
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Synthetic Thermo-Sensitive Hydrogel Microspheres as Temperature Probes in an Optical Tweezers Setup
Goren, S. et al.
2025
Chemistry Methods
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Tunable metastability of condensates reconciles their dual roles in amyloid fibril formation
Das, T. et al.
2025
Molecular Cell
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Bacterial RecD2 is a processive single-stranded DNA translocase with strand-switching capacity at DNA forks
Horme–o, S. et al.
2025
Nucleic Acids Research
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SARS-CoV-2 nucleocapsid protein directly prevents cGASÐDNA recognition through competitive binding
Gutmann, T. et al.
2025
PNAS
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Protocol for sample preparation and single-molecule optical tweezers study of nanodisc-embedded ABC transporter OpuA
van der Sleen, L. et al.
2025
STAR Protocols
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Real-Time Force Measurement Between Emulsion Droplets During Enzymatic Breakdown
Song, C. et al.
2025
JoVE
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Autoregulation of the real-time kinetics of the human mitochondrial replicative helicase
Plaza-G A, I. et al.
2025
Nature Communications
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Homotypic RNA clustering accompanies a liquid-to-solid transition inside the core of multi-component biomolecular condensates
Mahendran, T. S. et al.
2025
Nature Chemistry
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The mitotic chromosome periphery modulates chromosome mechanics
Mendonca, T. et al.
2025
Nature Communications
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Mechanism of Rad51 filament formation by Rad52 and Rad55-Rad57 in homologous recombination
Deveryshetty, J. et al.
2025
Nature Communications
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Stability of whey protein isolateÐchitosan Pickering emulsions and their application in mayonnaise
Tian, Z. et al.
2025
Discover Food
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Structural mechanism of strand exchange by the RAD51 filament
Joudeh, L. et al.
2025
eLife
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Arrest Peptide Profiling resolves co-translational folding pathways and chaperone interactions in vivo
Chen, X. et al.
2025
Nature Communications
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Trigger factor accelerates nascent chain compaction and folding
Till, K. et al.
2025
PNAS
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Substrate accessibility regulation of human TopIIa decatenation by cohesin
Cutts, E. E. et al.
2025
Nature Communications
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Optical tweezers investigation of storage stability in whey protein and chitosan_based pickering emulsions
Tian, Z. et al.
2025
Food Science & Biotechnology
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GAGA zinc finger transcription factor searches chromatin by 1DÐ3D facilitated diffusion
Feng, X. A. et al.
2025
Nature Structural & Molecular Biology
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Migrasome formation is initiated preferentially in tubular junctions by membrane tension
Zucker, B. et al.
2025
Biophysical Journal
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Extracellular domain 2 of TSPAN4 governs its functions
Dharan, R. et al.
2024
Biophysical Reports
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Optical tweezers-controlled hotspot for sensitive and reproducible surface-enhanced Raman spectroscopy characterization of native protein structures
Dai, X. et al.
2021
Nature Communications
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Identification and correction of miscalibration artifacts based on force noise for optical tweezers experiments
Freitag, M. et al.
2021
J. Chemical Physics
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Experimental study of a nanoscale translocation ratchet
Molcrette, B. et al.
2022
PNAS
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Supported Natural Membranes on Microspheres for Protein–Protein Interaction Studies
Cheppali, S. et al.
2022
ACS Appl. Mater. Interfaces
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Tetraspanin 4 stabilizes membrane swellings and facilitates their maturation into migrasomes
Dharan, R. et al.
2023
Nature Communications
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Membrane Tension Inhibits Lipid Mixing by Increasing the Hemifusion Stalk Energy
Shendrik, P. et al.
2023
ACS Nano
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Efficient optical plasmonic tweezer-controlled single-molecule SERS characterization of pH-dependent amylin species in aqueous milieus
Fu, F. et al.
2023
Nature Communications
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A circular zone of attachment to the extracellular matrix provides directionality to the motility of Toxoplasma gondii in 3D
Stadler, R. et al.
2022
eLife
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Single Cell Reactomics: Real‐Time Single‐Cell Activation Kinetics of Optically Trapped Macrophages
Vasse, G. F. et al.
2021
Small Methods
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3D nanofabricated soft microrobots with super-compliant picoforce springs as onboard sensors and actuators
Xu, H. et al.
2024
Nature Nanotechnology
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Single cell force spectroscopy of erythrocytes at physiological and febrile temperatures reveals mechano-modulatory effects of atorvastatin
Sheikhhassani, V. et al.
2022
Soft matter
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Single-cell analysis reveals chemokine-mediated differential regulation of monocyte mechanics
Evers, T. M. J. et al.
2022
iScience
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Single-Cell Mechanical Characterization of Human Macrophages
Evers, T. M. J. et al.
2022
Advanced Nanobiomed Research
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Weak catch bonds make strong networks
Mulla, Y. et al.
2022
Nature Materials
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Microtubule Lattice Spacing Governs Cohesive Envelope Formation of Tau Family Proteins
Siahaan, V. et al.
2022
Nature Chemical Biology
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Transmembrane proteins tetraspanin 4 and CD9 sense membrane curvature
Dharan, R. et al.
2022
PNAS
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Directed assembly of genetically engineered eukaryotic cells into living functional materials via ultrahigh-affinity protein interactions
Quikun, Y. et al.
2022
Science Advances
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Mechanics of serotonin-producing human entero-endocrine cells
Evers, T. M. J. et al.
2024
Mechanobiology in Medicine
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Probing Local Force Propagation in Tensed Fibrous Gels
Goren, S. et al.
2022
Small
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Construction of multiphasic membraneless organelles towards spontaneous spatial segregation and directional flow of biochemical reactions
Zhorabek, F. et al.
2023
Chemical Science
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Advanced glycation end-products as mediators of the aberrant crosslinking of extracellular matrix in scarred liver tissue
Lyu, C. et al.
2023
Nature Biomedical Engineering
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Cell protrusions and contractions generate long-range membrane tension propagation
De Belly, H. et al.
2023
Cell
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Dynamic encounters with red blood cells trigger splenic marginal zone B cell retention and function
Liu, D. et al.
2023
Nature Immunology
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Determination of single-molecule loading rate during mechanotransduction in cell adhesion
Jo, M.H. et al.
2024
Science
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Single-cell analysis of innate immune cell mechanics: an application to cancer immunology
Evers, T. M. J. et al.
2024
Material Advances
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Rethinking the relationships between gel like structure and sludge dewaterability based on a binary gel like structure model: Implications for the online sensing of dewaterability
Zhang, D. et al.
2024
Water Research
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Micro-tensile rheology of fibrous gels quantifies strain-dependent anisotropy
Goren, S. et al.
2024
Acta Biomaterialia
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Ebola Virus Glycoprotein Strongly Binds to Membranes in the Absence of Receptor Engagement
Vaknin, A. et al.
2024
ACS Infect. Dis.
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Mechano-inhibition of endocytosis sensitizes cancer cells to Fas-induced Apoptosis
Kural, M. H. et al.
2024
Cell Death & Disease
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Plasma membrane abundance dictates phagocytic capacity and functional cross-talk in myeloid cells
Winer, B. Y. et al.
2024
Science Immunology
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Salt-Dependent Rheology and Surface Tension of Protein Condensates Using Optical Traps
Jawerth, L. et al.
2018
Physical Review Letters
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Molecular Crowding Tunes Material States of Ribonucleoprotein Condensates
Kaur, T. et al.
2019
Biomolecules
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Structural basis for reversible amyloids of hnRNPA1 elucidates their role in stress granule assembly
Structural basis for reversible amyloids of hnRNPA1 elucidates their role in stress granule assembly
Gui, X., et al.
2019
Nature Communications
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Protein condensates as aging Maxwell fluids
Jawerth, L. et al.
2020
Science
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Interplay between Short-Range Attraction and Long-Range Repulsion Controls Reentrant Liquid Condensation of Ribonucleoprotein–RNA Complexes
Alshareedah, I. et al.
2019
Journal of the American Chemical Society
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Phase transition of RNA−protein complexes into ordered hollow condensates
Alshareedah, I. et al.
2020
PNAS
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A Minimal Load-and-Lock Ru Luminescent DNA Probe
Newton, M. D. et al.
2021
Angew. Chem. Int. Ed.
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Determinants for Fusion Speed of Biomolecular Droplets
Ghosh, A. et al.
2020
J. Phys. Chem. B
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Quantifying Viscosity and Surface Tension of Multi-Component Protein-Nucleic Acid Condensates
Alshareedah, I. et al.
2021
Biophysical Journal
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Sequence-encoded and Composition-dependent Protein-RNA Interactions Control Multiphasic Condensate Morphologies
Kaur, T. et al.
2021
Nature Communications
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Single-molecule and ensemble methods to probe RNP nucleation and condensate properties
Rhine, K. et al.
2021
Methods
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Direct visualization of the effect of DNA structure and ionic conditions on HU–DNA interactions
Lin, S. N. et al.
2021
Scientific Reports
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F/YGG-motif is an intrinsically disordered nucleic-acid binding motif
Van Lindt, J. et al.
2022
RNA biology
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Shear relaxation governs fusion dynamics of biomolecular condensates
Ghosh, A. et al.
2021
Nature Communications
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Programmable viscoelasticity in protein-RNA condensates with disordered sticker-spacer polypeptides
Alshareedah, I. et al.
2021
Nature Communications
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Controlling synthetic membraneless organelles by a red-light-dependent singlet oxygen-generating protein
Li, M. et al,
2022
Nature Communications
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Macromolecular Regulation of the Material Properties of Biomolecular Condensates
Kota, D. et al.
2022
J. Phys. Chem. Lett.
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Bloom syndrome helicase compresses single-stranded DNA into phase-separated condensates
Wang, T. et al.
2022
Angew. Chem. Int. Ed.
