z-Movi
For small-sizes Cell Avidity studies
A fast and simple solution for single-sample Cell Avidity experiments. Run up to 20 measurements per day.
Part of:
Up to 5 sequential Cell Avidity measurements on the same monolayer
Easy and flexible through quick set-up times and low investment
Fits in the smallest of labs and fume hoods
Platform
Small box, big impact
Discover what’s inside this tiny instrument
Acoustic force application
Automatically manages media exchanges and reagent additions, ensuring consistent and reproducible biology.
Fluorescence imaging
To capture Cell Avidity, the z-Movi utilizes fluorescence microscopy (635nm) to identify and track cell behavior throughout the force application.
Re-usable chip
Each z-Movi includes 5 re-usable chips that support up to 125 runs each. The chip allows for the creation of a robust monolayer and contains smart electronics to maintain consistent quality over its lifetime.
Temperature controlled
The z-Movi’s chip is temperature controlled, ensuring your experiments are consistently executed at the right conditions.
Workflow
Intuitive, from start to finish
Culture your target cells
Flow in your target cells and incubate between 2hrs to overnight, forming a uniform and robust monolayer in each chip.
Flow in your effectors
Introduce fluorescent effector cells or protein coated baeds. The z-Movi automatically takes care of the force application to ensure repeatable measurements.
Get real-time insights
Obtain preliminary Cell Avidity results right as the measurement happens, enabling immediate insights into possible binding behavior.
Grab your data and clean up
Visualize and analyze your data from the comfort of your desk or home. The re-usable chip can be cleaned using our standard cleaning protocols.
Software
Meet Oceon
Set up and execute your experiments with our easy-to-use interface
Oceon guides you through a full z-Movi experiment, making it very easy for new users to adopt. It keeps track of your experiments and chips, ensuring you maintain a clear overview.
Obtain unique insights through powerful analysis algorithms
Oceon’s real-time analysis provides immediate insight into binding. Its analysis algorithms identify cell behaviors, giving you a clear visualization of your results.
View, analyze and export your data anywhere, any time
Dive into your data and its analysis on your laptop or from behind your desk. Export your data to easily convert into figure-ready graphs. Oceon supports both Windows and Mac systems.
Key content
Discover all the details
z-Movi Product Brochure
Brochure
The latest all-in-one overview of our z-Movi solution.
Benefits
Beyond the product
Take a look at the perks that come with being one of our users
Symposia
Join the community
BIT (Breakthroughs in Immunology) is LUMICKS’ symposia format. We regularly host events across the world, aiming to bring together scientists interested in Cell Avidity applications to share their research, connect, and exchange ideas and experiences.
Begin your LUMICKS journey
Demonstrating value
Our application scientists can help create interest among potential users through organizing different events such as seminars, workshops, and demonstrations, as well as meet with stakeholders individually to understand and help solve their needs.
Avidigo services
At our Amsterdam headquarters, our internal Avidigo service team supports academic and industry clients looking to integrate Cell Avidity into their workflows and pipeline. From experimental design to data analysis and interpretation, we support you all the way.
Are you looking to gain proof before applying Cell Avidity?
Grant & tender support
Throughout our history we have supported multiple successful grants across a broad spectrum of funding and users involved. Our application scientists are experienced in highlighting the unique value of Cell Avidity and its solutions.
To this end, we have a dedicated grant expeditor brochure that indicates all the possibilities and provides a clear outline of the type of processes we can help you go through. Please contact us to gain more information!
To this end, we have a dedicated grant expeditor brochure that indicates all the possibilities and provides a clear outline of the type of processes we can help you go through. Please contact us to gain more information!
Let’s get in touch
Our team is standing by to help you
Technical note:
Filter CA shows 3 items
There is a hidden collection to add multiple authors to this publication.
This section is hidden when emtpy.
To keep everything visible here, that is being done outside the webflow designer from within Slater.
Filter CA shows 3 items
There is a hidden collection to add multiple authors to this publication.
This section is hidden when emtpy.
To keep everything visible here, that is being done outside the webflow designer from within Slater.
Text Link
Identification of potent biparatopic antibodies targeting FGFR2 fusion driven cholangiocarcinoma
Chaturantabut, S. et al.
2025
J. Clin. Investigation
https://www.jci.org/articles/view/182417
Publication
Text Link
Rational Chemical and Genetic Modifications Enhance Avidity and Function of CD70-Directed CAR T Cells for Myeloid Leukemia
Leick, M. B. et al.
2022
Cancer Cell
https://doi.org/10.1016/j.ccell.2022.04.001
Publication
Technical note:
Filter CA and show 4 Latest
This shows the most recent card of each resource type filtered on Business Unit CA.
Webinar, Scientific update, Whitepaper, Application note, Brochure.
We only show 4 and we have 6 types so the 2 older ones are hidden.
In design only 1 is shown, but the rest will be loaded when published.
Filter CA and show 4 Latest
This shows the most recent card of each resource type filtered on Business Unit CA.
Webinar, Scientific update, Whitepaper, Application note, Brochure.
We only show 4 and we have 6 types so the 2 older ones are hidden.
In design only 1 is shown, but the rest will be loaded when published.
Button Text
Improving CAR-T immunotherapy for lymphoma by fine-tuning avidity
Webinar
July 16, 2024
01-01-20
Commercial CAR-T therapies still suffer from severe limitations, as majority of patients fail to achieve complete response and ultimately relapse.
Watch this Webinar to discover Prof. Marco Ruella’s team have adopted a novel CAR-T avidity screening method to improve safety and exhaustion profile, leading to 100% clinical response in a phase I trial.
Text Link
Enhancing efficacy against clear cell renal cell carcinoma through format-tuning of bispecific T cell engagers
Scientific update
January 29, 2025
01-01-20
Cell Avidity: a key to accelerate IND filing in cell therapy drug development
Whitepaper
July 1, 2023
01-01-20
Cell Avidity measures true binding of biparatopic antibodies
Application note
April 23, 2025
01-01-20
Mechanistic issues limit the effectiveness of many current cancer-targeting antibody therapies, with monospecific antibodies often hindered by receptor dimerization and activation. Biparatopic antibodies, which bind to two unique non-overlapping epitopes, offer a promising solution with stronger binding, more potent antagonism, and higher specificity.
Avidigo Service Brochure
Brochure
May 1, 2025
01-01-20
SITC 2025
Conference
April 22, 2025
01-01-20
CAR-TCR Summit 2025
Conference
April 22, 2025
01-01-20
CICON 2025
Conference
April 22, 2025
01-01-20
See more. Know more.
We empower the academic and pharmaceutical communities with cutting-edge technologies to deeply understand the mechanisms of life and disease, driving the discovery and development of life-saving therapies
All products and technologies are for Research Use Only (RUO) except when specifically noted