Publications
Dynamic Single-Molecule
Thank you! Your submission has been received!
Oops! Something went wrong while submitting the form.
Thank you! Your submission has been received!
Oops! Something went wrong while submitting the form.
Kinesin-14 HSET and KlpA are non-processive microtubule motors with load-dependent power strokes
Liu, X. et al.
2024
Nature Communications
This is some text inside of a div block.
Processive extrusion of polypeptide loops by a Hsp100 disaggregase
Avellaneda, M. et al.
2020
Nature Communications
This is some text inside of a div block.
Simultaneous sensing and imaging of individual biomolecular complexes enabled by modular DNA–protein coupling
Avellaneda, M. et al.
2020
Communications Chemistry
This is some text inside of a div block.
Facile tethering of stable and unstable proteins for optical tweezers experiments
Maciuba, K. et al.
2021
Biophysical Journal
This is some text inside of a div block.
The ribosome modulates folding inside the ribosomal exit tunnel
Wruck, F. et al.
2021
Communications Biology
This is some text inside of a div block.
Optical Tweezers to Study RNA-Protein Interactions in Translation Regulatio
Pekarek, L. et al.
2022
JoVE
This is some text inside of a div block.
Minimalist design of polymer-oligopeptide hybrid as intrinsically disordered protein-mimicking scaffold for artificial membraneless organelle
Liu, J. et al.
2022
ACS Cent. Sci.
This is some text inside of a div block.
Protein chain collapse modulation and folding stimulation by GroEL-ES
Naqvi, M. et al.
2022
Science Advances
This is some text inside of a div block.
POTATO: An automated pipeline for batch analysis of optical tweezers data
Buck, S. et al.
2022
Biophysical Journal
This is some text inside of a div block.
Single-molecule experiments reveal the elbow as an essential folding guide in SMC coiled-coil arms
Freitag, M. et al.
2022
Biophysical Journal
This is some text inside of a div block.
The activated ClpP peptidase forcefully grips a protein substrate
Walker, S. D. et al.
2022
Biophysical Journal
This is some text inside of a div block.
Single-molecule force spectroscopy of toehold-mediated strand displacement
Walbrun, A. et al.
2024
Nature Communications
This is some text inside of a div block.
Cis-mediated interactions of the SARS-CoV-2 frameshift RNA alter its conformations and affect function
Pekarek, L. et al.
2022
NAR
This is some text inside of a div block.
Mechanistic Insights into the Folding Mechanism of Region V in Ice-Binding Protein Secreted by Marinomonas primoryensi Revealed by Single-Molecule Force Spectroscopy
Wang, H. et al.
2023
Langmuir
This is some text inside of a div block.
A molecular optomechanics approach reveals functional relevance of force transduction across talin and desmoplakin
Sadhanasatish, T. et al.
2023
Science Advances
This is some text inside of a div block.
Cytosolic Interactome Protects Against Protein Unfolding in a Single Molecule Experiment
Scalvini, B. et al.
2023
Advanced Biology
This is some text inside of a div block.
Free-energy measuring nanopore device
Gavrilov, M. et al.
2023
Physical Review E
This is some text inside of a div block.
Aha1 regulates Hsp90’s conformation and function in a stoichiometry-dependent way
Mondol, T. et al.
2023
Biophysical Journal
This is some text inside of a div block.
Membrane-induced 2D phase separation of the focal adhesion protein talin
Litschel, T. et al.
2024
Nature Communications
This is some text inside of a div block.
Probing the stability and interdomain interactions in the ABC transporter OpuA using single-molecule optical tweezers
Van Der Sleen, L. et al.
2024
Cell Reports
This is some text inside of a div block.
Stick-slip unfolding favors self-association of expanded HTT mRNA
O’Brien, B. M. et al.
2024
Nature Communications
This is some text inside of a div block.
Human RPA activates BLM’s bidirectional DNA unwinding from a nick
Qin, Z. et al.
2020
eLife
This is some text inside of a div block.
DNA stretching induces Cas9 off-target activity
Newton, M. D. et al.
2019
Nature Structural & Molecular Biology
This is some text inside of a div block.
Reversible histone glycation is associated with disease-related changes in chromatin architecture
Zheng, Q. et al.
2019
Nature Communications
This is some text inside of a div block.
Sites of high local frustration in DNA origami
Kosinski, R. et al.
2019
Nature Communications
This is some text inside of a div block.
Replication Fork Activation Is Enabled by a Single-Stranded DNA Gate in CMG Helicase
Wasserman, M. et al.
2019
Cell
This is some text inside of a div block.
Real-Time Assembly of Viruslike Nucleocapsids Elucidated at the Single-Particle Level
Marchetti, M. et al.
2019
Nano Letters
This is some text inside of a div block.
Single-Molecule Mechanics in Ligand Concentration Gradient
Kretzer, B. et al.
2020
Micromachines
This is some text inside of a div block.
Single-molecule and in silico dissection of the interaction between Polycomb repressive complex 2 and chromatin
Leicher, R. et al.
2019
PNAS
This is some text inside of a div block.
Cooperative DNA looping by PRC2 complexes
Lin, X. et al.
2021
Nucleic Acids Research
This is some text inside of a div block.
Alkyltransferase-like protein clusters scan DNA rapidly over long distances and recruit NER to alkyl-DNA lesions
Rill, N. et al.
2020
PNAS
This is some text inside of a div block.
Distinct pre-initiation steps in human mitochondrial translation
Khawaja, A. et al.
2020
Nature Communications
This is some text inside of a div block.
Constructing arrays of nucleosome positioning sequences using Gibson Assembly for single-molecule studies
Spakman, D. et al.
2020
Scientific Reports
This is some text inside of a div block.
Single-molecule analysis reveals cooperative stimulation of Rad51 filament nucleation and growth by mediator proteins
Belan, O. et al.
2021
Molecular Cell
This is some text inside of a div block.
Dynamics of Staphylococcus aureus Cas9 in DNA target Association and Dissociation
Zhang, S. et al.
2020
EMBO Rep
This is some text inside of a div block.
HP1 proteins compact DNA into mechanically and positionally stable phase separated domains
Keenen, M. M. et al.
2021
eLife
This is some text inside of a div block.
Proximal Single-Stranded RNA Destabilizes Human Telomerase RNA G-Quadruplex and Induces Its Distinct Conformers
Ye, S. et al.
2021
J. Phys. Chem. Lett.
This is some text inside of a div block.
Generation of versatile ss-dsDNA hybrid substrates for single-molecule analysis
Belan, O. et al.
2021
STAR Protocols
This is some text inside of a div block.
Mechanics of CRISPR-Cas12a and engineered variants on λ-DNA
Paul, B. et al.
2021
Nucleic Acids Research
This is some text inside of a div block.
Force generation by protein–DNA co-condensation
Quail, T. et al.
2021
Nature Physics
This is some text inside of a div block.
Elucidating the Role of Topological Constraint on the Structure of Overstretched DNA Using Fluorescence Polarization Microscopy
Backer, A. S. et al.
2021
J. Phys. Chem. B
This is some text inside of a div block.
CTP promotes efficient ParB-dependent DNA condensation by facilitating one-dimensional diffusion from parS
de Asis Balaguer, F. et al.
2021
eLife
This is some text inside of a div block.
Efficient DNA interrogation of SpCas9 governed by its electrostatic interaction with DNA beyond the PAM and protospacer
Zhang, Q. et al.
2021
Nucleic Acids Research
This is some text inside of a div block.
Virus self-assembly proceeds through contact-rich energy minima
Buzón, P. et al.
2021
Science Advances
This is some text inside of a div block.
Structural and molecular basis for Cardiovirus 2A protein as a viral gene expression switch
Hill, C. H. et al.
2021
Nature Communications
This is some text inside of a div block.
DNA replication origins retain mobile licensing proteins
Sánchez, H. et al.
2021
Nature Communications
This is some text inside of a div block.
Human HELB is a processive motor protein that catalyzes RPA clearance from single-stranded DNA
Hormeno, S. et al.
2022
eLife
This is some text inside of a div block.
HELQ is a dual-function DSB repair enzyme modulated by RPA and RAD51
Anand, R. et al.
2021
Nature Communications
This is some text inside of a div block.
Cas12a Target Search and Cleavage on Force-Stretched DNA
Losito, M. et al.
2021
PCCP
This is some text inside of a div block.
CENP-B-mediated DNA loops regulate activity and stability of human centromeres
Chardon, F. et al.
2022
Molecular Cell
This is some text inside of a div block.
Co-condensation of proteins with single- and double-stranded DNA
Renger, R. et al.
2022
PNAS
This is some text inside of a div block.
HIV-1 Nucleocapsid Protein Binds Double-Stranded DNA in Multiple Modes to Regulate Compaction and Capsid Uncoating
Gien, H. et al.
2022
Viruses
This is some text inside of a div block.
Identification of the target and mode of action for the prokaryotic nucleotide excision repair inhibitor ATBC
Bernacchia, L. et al.
2022
Biosci Rep
This is some text inside of a div block.
Sequence-dependent surface condensation of a pioneer transcription factor on DNA
Morin, J. A. et al.
2022
Nature Physics
This is some text inside of a div block.
The convergence of head-on DNA unwinding forks induces helicase oligomerization and activity transition
Bi, L. et al.
2022
PNAS
This is some text inside of a div block.
Resolving the subtle details of human DNA alkyltransferase lesion search and repair mechanism by single-molecule studies
Kono, S. et al.
2022
PNAS
This is some text inside of a div block.
Rtt105 regulates RPA function by configurationally stapling the flexible domains
Kuppa, S. et al.
2022
Nature Communications
This is some text inside of a div block.
Stochastically multimerized ParB orchestrates DNA assembly as unveiled by single-molecule analysis
Guo, L. et al.
2022
Nucleic Acids Research
This is some text inside of a div block.
Nucleosome-directed replication origin licensing independent of a consensus DNA sequence
Li, S. et al.
2022
Nature Communications
This is some text inside of a div block.
Origin recognition complex harbors an intrinsic nucleosome remodeling activity
Li, S. et al.
2022
PNAS
This is some text inside of a div block.
ATP Binding Facilitates Target Search of SWR1 Chromatin Remodeler by Promoting One-Dimensional Diffusion on DNA
Carcamo, C. C. et al.
2022
eLife
This is some text inside of a div block.
Single-molecule analysis of DNA-binding proteins from nuclear extracts (SMADNE)
Schaich, M. et al.
2023
NAR
This is some text inside of a div block.
Search and processing of Holliday junctions within long DNA by junction-resolving enzymes
Kaczmarczyk, A. et al.
2022
Nature Communications
This is some text inside of a div block.
Smc5/6’s multifaceted DNA binding capacities stabilize branched DNA structures
Chang, J. T-H. et al.
2022
Nature Communications
This is some text inside of a div block.
Head-on and co-directional RNA polymerase collisions orchestrate bidirectional transcription termination
Wang, L. et. al.
2023
Molecular Cell
This is some text inside of a div block.
POLQ seals post-replicative ssDNA gaps to maintain genome stability in BRCA-deficient cancer cells
Belan, O. et al.
2022
Molecular Cell
This is some text inside of a div block.
PICH acts as a force dependent nucleosome remodeler
Spakman, D. et al.
2022
Nature Communications
This is some text inside of a div block.
Unlicensed origin DNA melting by MCV and SV40 polyomavirus LT proteins is independent of ATP-dependent helicase activity
Wan, L. et al.
2023
PNAS
This is some text inside of a div block.
Cooperative interaction between AAG and UV-DDB in the removal of modified bases
Jang, S. et al.
2022
NAR
This is some text inside of a div block.
Single-Molecule Force Spectroscopy of Deoxyribonucleic Acid and Deoxyribonucleic Acid Polymerase Activity Impacted by Alkylating Agents
Cai, T. et al.
2023
J. Phys. Chem. Lett.
This is some text inside of a div block.
Human FACT subunits coordinate to catalyze both disassembly and reassembly of nucleosomes
McCauley, M. et al.
2022
Cell Reports
This is some text inside of a div block.
Stabilization of DNA fork junctions by Smc5/6 complexes revealed by single-molecule imaging
Tanasie, N-L. et al.
2022
Cell Reports
This is some text inside of a div block.
Nucleotide binding halts diffusion of the eukaryotic replicative helicase during activation
Montero, D. R. et al.
2023
Nature Communications
This is some text inside of a div block.
Establishment of dsDNA-dsDNA interactions by the condensin complex
Tang, M. et al.
2023
Molecular Cell
This is some text inside of a div block.
“Helicase” activity promoted through dynamic interactions between a ssDNA translocase and a diffusing SSB protein
Mersch, K. N. et al.
2023
PNAS
This is some text inside of a div block.
Structure and function of the RAD51BCD-XRCC2 tumour suppressor complex
Greenhough, L. A. et al.
2023
Nature Communications
This is some text inside of a div block.
Visualization of direct and diffusion-assisted RAD51 nucleation by full-length human BRCA2 protein
Belan, O. et al.
2023
Molecular Cell
This is some text inside of a div block.
RNase H1 facilitates recombinase recruitment by degrading DNA–RNA hybrids during meiosis
Liu, C. et al.
2023
Nucleic Acids Research
This is some text inside of a div block.
Negative DNA supercoiling induces genome-wide Cas9 off-target activity
Newton, M. D. et al.
2023
Molecular Cell
This is some text inside of a div block.
Assembly mechanism of the inflammasome sensor AIM2 revealed by single molecule analysis
Sharma, M. et al.
2023
Nature Communications
This is some text inside of a div block.
E. coli RecB Nuclease Domain Regulates RecBCD Helicase Activity but not Single Stranded DNA Translocase Activity
Fazio, N. et al.
2024
J. Molecular Biology
This is some text inside of a div block.
Joint Efforts of Replicative Helicase and SSB Ensure Inherent Replicative Tolerance of G-Quadruplex
Guo, L. et al.
2023
Advanced Science
This is some text inside of a div block.
A chromatinized origin reduces the mobility of ORC and MCM through interactions and spatial constraint
Sánchez, H. et al.
2023
Nature Communications
This is some text inside of a div block.
The Histone Chaperones SET/TAF‐1β and NPM1 Exhibit Conserved Functionality in Nucleosome Remodeling and Histone Eviction in a Cytochrome c ‐Dependent Manner
Buzón, P. et al.
2023
Advanced Science
This is some text inside of a div block.
DNA binding and bridging by human CtIP in the healthy and diseased states
Lokanathan Balaji, S. et al.
2024
Nucleic Acids Research
This is some text inside of a div block.
Single-molecule analysis of purified proteins and nuclear extracts: Insights from 8-oxoguanine glycosylase 1
Schaich, M.A. et al.
2024
DNA Repair
This is some text inside of a div block.
De novo fabrication of custom-sequence plasmids for the synthesis of long DNA constructs with extrahelical features
Montero, D. R. et al.,
2023
Biophysical Journal
This is some text inside of a div block.
Developing novel antimicrobials by combining cancer chemotherapeutics with bacterial DNA repair inhibitors
Bernacchia, L. et al.
2023
Plos Pathogens
This is some text inside of a div block.
PARP1-DNA co-condensation drives DNA repair site assembly to prevent disjunction of broken DNA ends
Chappidi, N. et al.
2024
Cell
This is some text inside of a div block.
Rapid Long-distance Migration of RPA on Single Stranded DNA Occurs Through Intersegmental Transfer Utilizing Multivalent Interactions
Pangeni, S. et al.
2024
J. Molecular Biology
This is some text inside of a div block.
Differential dynamics specify MeCP2 function at nucleosomes and methylated DNA
Chua, G. et al.
2024
Nature Structural & Molecular Biology
This is some text inside of a div block.
Dynamic 1D Search and Processive Nucleosome Translocations by RSC and ISW2 Chromatin Remodelers
Kim, J. M. et al.
2024
eLife
This is some text inside of a div block.
A Biophysics Toolbox for Reliable Data Acquisition and Processing in Integrated Force–Confocal Fluorescence Microscopy
Liu, Z. et al.
2024
ACS Photonics
This is some text inside of a div block.
TMPyP binding evokes a complex, tunable nanomechanical response in DNA
Kretzer, B. et al.
2024
Nucleic Acids Research
This is some text inside of a div block.
ISWI catalyzes nucleosome sliding in condensed nucleosome arrays
Vizjak, P. et al.
2024
Nature Structural & Molecular Biology
This is some text inside of a div block.
FANCD2–FANCI surveys DNA and recognizes double- to single-stranded junctions
Alcón, P. et al.
2024
Nature
This is some text inside of a div block.
RPA transforms RNase H1 to a bidirectional exoribonuclease for processive RNA–DNA hybrid cleavage
Li, Y. et al.
2024
Nature Communications
This is some text inside of a div block.
How to scan naked DNA using promiscuous recognition and no clamping: a model for pioneer transcription factors
Goluguri, R. et al.
2024
Nucleic Acids Research
This is some text inside of a div block.
Thymine DNA glycosylase combines sliding, hopping, and nucleosome interactions to efficiently search for 5-formylcytosine
Schnable, B. et al.
2024
Nature Communications
This is some text inside of a div block.
The human Shu complex promotes RAD51 activity by modulating RPA dynamics on ssDNA
Hengel, S. et al.
2024
Nature Communications
This is some text inside of a div block.
There’s nothing here!
Try using a different combination of search criteria