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Publications

Dynamic Single-Molecule
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Cooperative interaction between AAG and UV-DDB in the removal of modified bases
Cooperative interaction between AAG and UV-DDB in the removal of modified bases
Jang, S. et al.
2022
NAR
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DNA Repair
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Single-Molecule Force Spectroscopy of Deoxyribonucleic Acid and Deoxyribonucleic Acid Polymerase Activity Impacted by Alkylating Agents
Single-Molecule Force Spectroscopy of Deoxyribonucleic Acid and Deoxyribonucleic Acid Polymerase Activity Impacted by Alkylating Agents
Cai, T. et al.
2023
J. Phys. Chem. Lett.
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DNA/RNA Structure
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Human FACT subunits coordinate to catalyze both disassembly and reassembly of nucleosomes
Human FACT subunits coordinate to catalyze both disassembly and reassembly of nucleosomes
McCauley, M. et al.
2022
Cell Reports
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DNA Organization
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Stabilization of DNA fork junctions by Smc5/6 complexes revealed by single-molecule imaging
Stabilization of DNA fork junctions by Smc5/6 complexes revealed by single-molecule imaging
Tanasie, N-L. et al.
2022
Cell Reports
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DNA Organization
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Nucleotide binding halts diffusion of the eukaryotic replicative helicase during activation
Nucleotide binding halts diffusion of the eukaryotic replicative helicase during activation
Montero, D. R. et al.
2023
Nature Communications
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DNA Replication
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Establishment of dsDNA-dsDNA interactions by the condensin complex
Establishment of dsDNA-dsDNA interactions by the condensin complex
Tang, M. et al.
2023
Molecular Cell
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DNA Organization
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“Helicase” activity promoted through dynamic interactions between a ssDNA translocase and a diffusing SSB protein
“Helicase” activity promoted through dynamic interactions between a ssDNA translocase and a diffusing SSB protein
Mersch, K. N. et al.
2023
PNAS
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DNA Repair
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Structure and function of the RAD51BCD-XRCC2 tumour suppressor complex
Structure and function of the RAD51BCD-XRCC2 tumour suppressor complex
Greenhough, L. A. et al.
2023
Nature Communications
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DNA Repair
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Visualization of direct and diffusion-assisted RAD51 nucleation by full-length human BRCA2 protein
Visualization of direct and diffusion-assisted RAD51 nucleation by full-length human BRCA2 protein
Belan, O. et al.
2023
Molecular Cell
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DNA Repair
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RNase H1 facilitates recombinase recruitment by degrading DNA–RNA hybrids during meiosis
RNase H1 facilitates recombinase recruitment by degrading DNA–RNA hybrids during meiosis
Liu, C. et al.
2023
Nucleic Acids Research
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DNA/RNA Structure
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Negative DNA supercoiling induces genome-wide Cas9 off-target activity
Negative DNA supercoiling induces genome-wide Cas9 off-target activity
Newton, M. D. et al.
2023
Molecular Cell
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DNA Editing
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Assembly mechanism of the inflammasome sensor AIM2 revealed by single molecule analysis
Assembly mechanism of the inflammasome sensor AIM2 revealed by single molecule analysis
Sharma, M. et al.
2023
Nature Communications
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DNA-Binding proteins
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E. coli RecB Nuclease Domain Regulates RecBCD Helicase Activity but not Single Stranded DNA Translocase Activity
E. coli RecB Nuclease Domain Regulates RecBCD Helicase Activity but not Single Stranded DNA Translocase Activity
Fazio, N. et al.
2024
Journal of Molecular Biology
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DNA Replication
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Joint Efforts of Replicative Helicase and SSB Ensure Inherent Replicative Tolerance of G-Quadruplex
Joint Efforts of Replicative Helicase and SSB Ensure Inherent Replicative Tolerance of G-Quadruplex
Guo, L. et al.
2023
Advanced Science
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DNA Replication
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A chromatinized origin reduces the mobility of ORC and MCM through interactions and spatial constraint
A chromatinized origin reduces the mobility of ORC and MCM through interactions and spatial constraint
Sánchez, H. et al.
2023
Nature Communications
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DNA Organization
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The Histone Chaperones SET/TAF‐1β and NPM1 Exhibit Conserved Functionality in Nucleosome Remodeling and Histone Eviction in a Cytochrome c ‐Dependent Manner
The Histone Chaperones SET/TAF‐1β and NPM1 Exhibit Conserved Functionality in Nucleosome Remodeling and Histone Eviction in a Cytochrome c ‐Dependent Manner
Buzón, P. et al.
2023
Advanced Science
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DNA Organization
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DNA binding and bridging by human CtIP in the healthy and diseased states
DNA binding and bridging by human CtIP in the healthy and diseased states
Lokanathan Balaji, S. et al.
2024
Nucleic Acids Research
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DNA Repair
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Single-molecule analysis of purified proteins and nuclear extracts: Insights from 8-oxoguanine glycosylase 1
Single-molecule analysis of purified proteins and nuclear extracts: Insights from 8-oxoguanine glycosylase 1
Schaich, M.A. et al.
2024
DNA Repair
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DNA Repair
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De novo fabrication of custom-sequence plasmids for the synthesis of long DNA constructs with extrahelical features
De novo fabrication of custom-sequence plasmids for the synthesis of long DNA constructs with extrahelical features
Montero, D. R. et al.,
2023
Biophysical Journal
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DNA Replication
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Developing novel antimicrobials by combining cancer chemotherapeutics with bacterial DNA repair inhibitors
Developing novel antimicrobials by combining cancer chemotherapeutics with bacterial DNA repair inhibitors
Bernacchia, L. et al.
2023
Plos Pathogens
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DNA Repair
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PARP1-DNA co-condensation drives DNA repair site assembly to prevent disjunction of broken DNA ends
PARP1-DNA co-condensation drives DNA repair site assembly to prevent disjunction of broken DNA ends
Chappidi, N. et al.
2024
Cell
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DNA-Binding proteins
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Rapid Long-distance Migration of RPA on Single Stranded DNA Occurs Through Intersegmental Transfer Utilizing Multivalent Interactions
Rapid Long-distance Migration of RPA on Single Stranded DNA Occurs Through Intersegmental Transfer Utilizing Multivalent Interactions
Pangeni, S. et al.
2024
Journal of Molecular Biology
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DNA Repair
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Differential dynamics specify MeCP2 function at nucleosomes and methylated DNA
Differential dynamics specify MeCP2 function at nucleosomes and methylated DNA
Chua, G. et al.
2024
Nature Structural & Molecular Biology
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DNA Organization
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Dynamic 1D Search and Processive Nucleosome Translocations by RSC and ISW2 Chromatin Remodelers
Dynamic 1D Search and Processive Nucleosome Translocations by RSC and ISW2 Chromatin Remodelers
Kim, J. M. et al.
2024
eLife
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DNA Organization
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A Biophysics Toolbox for Reliable Data Acquisition and Processing in Integrated Force–Confocal Fluorescence Microscopy
A Biophysics Toolbox for Reliable Data Acquisition and Processing in Integrated Force–Confocal Fluorescence Microscopy
Liu, Z. et al.
2024
ACS Photonics
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Text Link
TMPyP binding evokes a complex, tunable nanomechanical response in DNA
TMPyP binding evokes a complex, tunable nanomechanical response in DNA
Kretzer, B. et al.
2024
Nucleic Acids Research
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DNA/RNA Structure
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ISWI catalyzes nucleosome sliding in condensed nucleosome arrays
ISWI catalyzes nucleosome sliding in condensed nucleosome arrays
Vizjak, P. et al.
2024
Nature Structural & Molecular Biology
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DNA Organization
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FANCD2–FANCI surveys DNA and recognizes double- to single-stranded junctions
FANCD2–FANCI surveys DNA and recognizes double- to single-stranded junctions
Alcón, P. et al.
2024
Nature
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DNA Repair
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RPA transforms RNase H1 to a bidirectional exoribonuclease for processive RNA–DNA hybrid cleavage
RPA transforms RNase H1 to a bidirectional exoribonuclease for processive RNA–DNA hybrid cleavage
Li, Y. et al.
2024
Nature Communications
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DNA Repair
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How to scan naked DNA using promiscuous recognition and no clamping: a model for pioneer transcription factors
How to scan naked DNA using promiscuous recognition and no clamping: a model for pioneer transcription factors
Goluguri, R. et al.
2024
Nucleic Acids Research
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DNA Transcription
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Thymine DNA glycosylase combines sliding, hopping, and nucleosome interactions to efficiently search for 5-formylcytosine
Thymine DNA glycosylase combines sliding, hopping, and nucleosome interactions to efficiently search for 5-formylcytosine
Schnable, B. et al.
2024
Nature Communications
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DNA Repair
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The human Shu complex promotes RAD51 activity by modulating RPA dynamics on ssDNA
The human Shu complex promotes RAD51 activity by modulating RPA dynamics on ssDNA
Hengel, S. et al.
2024
Nature Communications
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DNA Repair
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Probing the mechanism of nick searching by LIG1 at the single-molecule level
Probing the mechanism of nick searching by LIG1 at the single-molecule level
Chatterjee, S. et al.
2024
Nucleic Acids Research
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DNA Repair
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Protamine-Mediated Tangles Produce Extreme Deoxyribonucleic Acid Compaction
Protamine-Mediated Tangles Produce Extreme Deoxyribonucleic Acid Compaction
Ahlawat, V. et al.
2024
JACS
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DNA Organization
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