Publications
Dynamic Single-Molecule
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CENP-B-mediated DNA loops regulate activity and stability of human centromeres
Chardon, F. et al.
2022
Molecular Cell
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Co-condensation of proteins with single- and double-stranded DNA
Renger, R. et al.
2022
PNAS
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HIV-1 Nucleocapsid Protein Binds Double-Stranded DNA in Multiple Modes to Regulate Compaction and Capsid Uncoating
Gien, H. et al.
2022
Viruses
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Identification of the target and mode of action for the prokaryotic nucleotide excision repair inhibitor ATBC
Bernacchia, L. et al.
2022
Biosci Rep
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Sequence-dependent surface condensation of a pioneer transcription factor on DNA
Morin, J. A. et al.
2022
Nature Physics
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The convergence of head-on DNA unwinding forks induces helicase oligomerization and activity transition
Bi, L. et al.
2022
PNAS
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Resolving the subtle details of human DNA alkyltransferase lesion search and repair mechanism by single-molecule studies
Kono, S. et al.
2022
PNAS
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Rtt105 regulates RPA function by configurationally stapling the flexible domains
Kuppa, S. et al.
2022
Nature Communications
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Stochastically multimerized ParB orchestrates DNA assembly as unveiled by single-molecule analysis
Guo, L. et al.
2022
Nucleic Acids Research
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Nucleosome-directed replication origin licensing independent of a consensus DNA sequence
Li, S. et al.
2022
Nature Communications
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Origin recognition complex harbors an intrinsic nucleosome remodeling activity
Li, S. et al.
2022
PNAS
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ATP Binding Facilitates Target Search of SWR1 Chromatin Remodeler by Promoting One-Dimensional Diffusion on DNA
Carcamo, C. C. et al.
2022
eLife
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Single-molecule analysis of DNA-binding proteins from nuclear extracts (SMADNE)
Schaich, M. et al.
2023
NAR
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Search and processing of Holliday junctions within long DNA by junction-resolving enzymes
Kaczmarczyk, A. et al.
2022
Nature Communications
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Smc5/6’s multifaceted DNA binding capacities stabilize branched DNA structures
Chang, J. T-H. et al.
2022
Nature Communications
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Head-on and co-directional RNA polymerase collisions orchestrate bidirectional transcription termination
Wang, L. et. al.
2023
Molecular Cell
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POLQ seals post-replicative ssDNA gaps to maintain genome stability in BRCA-deficient cancer cells
Belan, O. et al.
2022
Molecular Cell
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PICH acts as a force dependent nucleosome remodeler
Spakman, D. et al.
2022
Nature Communications
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Unlicensed origin DNA melting by MCV and SV40 polyomavirus LT proteins is independent of ATP-dependent helicase activity
Wan, L. et al.
2023
PNAS
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Cooperative interaction between AAG and UV-DDB in the removal of modified bases
Jang, S. et al.
2022
NAR
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Single-Molecule Force Spectroscopy of Deoxyribonucleic Acid and Deoxyribonucleic Acid Polymerase Activity Impacted by Alkylating Agents
Cai, T. et al.
2023
J. Phys. Chem. Lett.
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Human FACT subunits coordinate to catalyze both disassembly and reassembly of nucleosomes
McCauley, M. et al.
2022
Cell Reports
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Stabilization of DNA fork junctions by Smc5/6 complexes revealed by single-molecule imaging
Tanasie, N-L. et al.
2022
Cell Reports
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Nucleotide binding halts diffusion of the eukaryotic replicative helicase during activation
Montero, D. R. et al.
2023
Nature Communications
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Establishment of dsDNA-dsDNA interactions by the condensin complex
Tang, M. et al.
2023
Molecular Cell
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“Helicase” activity promoted through dynamic interactions between a ssDNA translocase and a diffusing SSB protein
Mersch, K. N. et al.
2023
PNAS
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Structure and function of the RAD51BCD-XRCC2 tumour suppressor complex
Greenhough, L. A. et al.
2023
Nature Communications
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Visualization of direct and diffusion-assisted RAD51 nucleation by full-length human BRCA2 protein
Belan, O. et al.
2023
Molecular Cell
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RNase H1 facilitates recombinase recruitment by degrading DNA–RNA hybrids during meiosis
Liu, C. et al.
2023
Nucleic Acids Research
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Negative DNA supercoiling induces genome-wide Cas9 off-target activity
Newton, M. D. et al.
2023
Molecular Cell
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Assembly mechanism of the inflammasome sensor AIM2 revealed by single molecule analysis
Sharma, M. et al.
2023
Nature Communications
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E. coli RecB Nuclease Domain Regulates RecBCD Helicase Activity but not Single Stranded DNA Translocase Activity
Fazio, N. et al.
2024
J. Molecular Biology
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Joint Efforts of Replicative Helicase and SSB Ensure Inherent Replicative Tolerance of G-Quadruplex
Guo, L. et al.
2023
Advanced Science
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A chromatinized origin reduces the mobility of ORC and MCM through interactions and spatial constraint
Sánchez, H. et al.
2023
Nature Communications
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The Histone Chaperones SET/TAF‐1β and NPM1 Exhibit Conserved Functionality in Nucleosome Remodeling and Histone Eviction in a Cytochrome c ‐Dependent Manner
Buzón, P. et al.
2023
Advanced Science
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DNA binding and bridging by human CtIP in the healthy and diseased states
Lokanathan Balaji, S. et al.
2024
Nucleic Acids Research
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Single-molecule analysis of purified proteins and nuclear extracts: Insights from 8-oxoguanine glycosylase 1
Schaich, M.A. et al.
2024
DNA Repair
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De novo fabrication of custom-sequence plasmids for the synthesis of long DNA constructs with extrahelical features
Montero, D. R. et al.,
2023
Biophysical Journal
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Developing novel antimicrobials by combining cancer chemotherapeutics with bacterial DNA repair inhibitors
Bernacchia, L. et al.
2023
Plos Pathogens
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PARP1-DNA co-condensation drives DNA repair site assembly to prevent disjunction of broken DNA ends
Chappidi, N. et al.
2024
Cell
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Rapid Long-distance Migration of RPA on Single Stranded DNA Occurs Through Intersegmental Transfer Utilizing Multivalent Interactions
Pangeni, S. et al.
2024
J. Molecular Biology
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Differential dynamics specify MeCP2 function at nucleosomes and methylated DNA
Chua, G. et al.
2024
Nature Structural & Molecular Biology
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Dynamic 1D Search and Processive Nucleosome Translocations by RSC and ISW2 Chromatin Remodelers
Kim, J. M. et al.
2024
eLife
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A Biophysics Toolbox for Reliable Data Acquisition and Processing in Integrated Force–Confocal Fluorescence Microscopy
Liu, Z. et al.
2024
ACS Photonics
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TMPyP binding evokes a complex, tunable nanomechanical response in DNA
Kretzer, B. et al.
2024
Nucleic Acids Research
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ISWI catalyzes nucleosome sliding in condensed nucleosome arrays
Vizjak, P. et al.
2024
Nature Structural & Molecular Biology
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FANCD2–FANCI surveys DNA and recognizes double- to single-stranded junctions
Alcón, P. et al.
2024
Nature
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RPA transforms RNase H1 to a bidirectional exoribonuclease for processive RNA–DNA hybrid cleavage
Li, Y. et al.
2024
Nature Communications
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How to scan naked DNA using promiscuous recognition and no clamping: a model for pioneer transcription factors
Goluguri, R. et al.
2024
Nucleic Acids Research
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Thymine DNA glycosylase combines sliding, hopping, and nucleosome interactions to efficiently search for 5-formylcytosine
Schnable, B. et al.
2024
Nature Communications
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The human Shu complex promotes RAD51 activity by modulating RPA dynamics on ssDNA
Hengel, S. et al.
2024
Nature Communications
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Probing the mechanism of nick searching by LIG1 at the single-molecule level
Chatterjee, S. et al.
2024
Nucleic Acids Research
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Protamine-Mediated Tangles Produce Extreme Deoxyribonucleic Acid Compaction
Ahlawat, V. et al.
2024
JACS
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