This is a success message.

This is an error message.

This is also an error message.

Symposium

SMBio 2026 Sheffield

Single molecules. Joint research.

Start - end date

Sheffield, UK

The Diamond, 32 Leavygreave Rd, Broomhall, Sheffield S3 7RD

Welcome to a new Symposium

We are pleased to announce the SMBio26, the third UK-Ireland symposium focusing on single-molecule research! Featuring keynotes, talks, posters and discussions, this 2-day event aims to bring together scientists interested in single-molecule approaches to biology from all over the UK and Ireland to share their research, connect, and exchange ideas and experiences. Please join the registration list by filling out the form at the bottom of the page.

Organized by

Mina Brett-Pitt, PhD

Senior Sales Manager

LUMICKS

Matthew Newton, PhD

Research fellow

University of Sheffield

Ruby Peters, PhD

Physics of Life Early Career Fellow

University of Sheffield

Alice Pyne, PhD

Professor of Biophysics

University of Sheffield

Brought to you by

Invited speakers

Gijs Wuite, PhD

Professor

Vrije Universiteit Amsterdam

Sandrine Lévêque-Fort, PhD

CNRS Researcher Director

Paris Saclay University

Julie Welburn, PhD

Personal Chair in Mechanistic Cell Biology

University of Edinburgh

Andrew Kellett, PhD

Professor of Inorganic and Medicinial Chemistry

Dublin City University

Michelle Peckham, PhD

Professor of Cell Biology

University of Leeds

Aakash Basu, PhD

Assistant Professor

Durham University

Preliminary agenda

Start / End times:

Wednesday May 20 2026 - From 12:00 to 18:30

Thursday May 21 2026 - From 08:30 to 15:00

‍

| Day 1 | Wednesday May 20th | | ----------- | ----- | | 12:00 - 12:25 | Registration – LUMICKS | | 12:25 - 12:30 | Welcome from organisers | | | **Session 1** | | 12:30 - 12:45 | **The Endonuclease ANKLE1 Is Stimulated by Tension in DNA to Process Ultrafine Bridges**, Korak Kumar Ray, MRC‑LMS | | 12:45 - 13:00 | **SMC5/6 Binds to p‑DNA‑Like Structures in Positively Supercoiled DNA**, Anno Koetje, MRC‑LMS | | 13:00 - 13:15 | **A Molecular Trigger for Replication Fork Collapse**, Cameron McClymont, The Francis Crick Institute | | 13:15 - 13:30 | **Transitional Kinetics Between Open and Closed Helicase Structures Tuned by Salt via Intermediate States**, Mark Leake, University of York | | 13:30 - 13:40 | Sponsor Talk – **LUMICKS** | | 13:40 - 14:10 | **Invited Speaker: Studying Mitotic Motors from Single-Molecule to Cellular Level**, Julie Welburn, University of Edinburgh | | 14:10 - 14:30 | Coffee Break | | | **Session 2** | | 14:30 - 14:45 | **Label-Free Detection and Profiling of Individual Solution-Phase Molecules**, Lisa‑Maria Needham, University of Cambridge | | 14:45 - 15:00 | **Volumetric Single-Molecule Tracking Inside Subcellular Structures**, Sam Daly, University of Cambridge | | 15:00 - 15:15 | **Modular DNA Nanosensors Enable State-Aware Multiplexed Single-Molecule Mass Photometry in Complex Media**, Seham Helmi, University of Oxford | | 15:15 - 15:30 | **Nuclear Myosin VI Anchors DNA Ends to Promote Efficient Double-Strand Break Repair**, Chris Toseland, University of Sheffield | | 15:30 - 16:00 | **Invited Speaker: Probing Sequence-Specific Metallodrug–DNA Interactions at the Single-Molecule Level**, Andrew Kellett, Dublin City University | | 16:00 - 16:30 | Coffee Break | | | **Keynote Session** | | 16:30 - 17:30 | **Time-Modulated Illumination for Enhanced Single-Molecule Localization Microscopy**, Sandrine Lévêque‑Fort, Paris Saclay University | | 17:30 - 18:30 | Poster Session 1 & Drinks Reception | | 19:00 - | Dinner |

‍

| Day 2 | Thursday May 21st | | ----- | ----- | | 08:30 - 09:00 | Coffee | | | **Session 3** | | 09:00 - 09:15 | **Revealing Biological Structure and Heterogeneity with Deep Learning**, Susan Cox, King’s College London | | 09:15 - 09:30 | **Highly Multiplexed Single-Molecule Biomarker Detection Using Nanopores and Machine Learning**, Caroline Koch, Imperial College London | | 09:30 - 09:45 | **TopoStats2: Developing a Robust Tracing Software for Complex DNA Molecules**, Sylvie Whittle, University of Sheffield | | 09:45 - 09:55 | Sponsor Talk – **Exciting Instruments** | | 09:55 - 10:25 | **Invited Speaker: Imaging the Cytoskeleton**, Michelle Peckham, University of Leeds | | 10:30 - 11:00 | Coffee Break | | | **Session 4** | | 11:00 - 11:15 | **Direct Observation of ATP-Driven Ubiquitin Chain Handling by Cdc48**, Dhawal Choudhary, AMOLF Amsterdam | | 11:15 - 11:30 | **Structure and Function of the Mitochondrial DNA Network in Trypanosomatid Parasites**, Lirong Jiang, Institute of Immunology & Infection Research, University of Edinburgh | | 11:30 - 11:45 | **Mechanics That Underpin the Filament Assembly of the IFI16 Immune Sensor**, Jungsan Sohn, Johns Hopkins School of Medicine | | 11:45 - 12:00 | **Oligomerisation of Kinetochore Complexes Controls Microtubule Dynamics**, Vladimir Volkov, Queen Mary University of London | | 12:00 - 12:30 | **Invited Speaker: Sequence-Dependent Control of DNA Supercoiling by DNA Gyrase**, Aakash Basu, University of Durham | | 12:30 - 13:30 | Lunch, Posters and Coffee | | | **Keynote Session** | | 13:30 - 14:30 | **Elucidating the Mechanics and Structure of Whole Mitotic Chromosomes**, Gijs Wuite, VU Amsterdam | | 14:30 - 14:45 | Closing Remarks and Poster Prizes | | 14:45 - | End |

Day 1, Monday 17 March
12:30 - 1:00 PM	Registration and coffee/snacks
12:30 - 1:00 PM	Registration and coffee/snacks
12:30 - 1:00 PM	Registration and coffee/snacks

Day 1, Monday 17 March
12:30 - 1:00 PM	Registration and coffee/snacks
12:30 - 1:00 PM	Registration and coffee/snacks
12:30 - 1:00 PM	Registration and coffee/snacks

Day 1, Monday 17 March
12:30 - 1:00 PM	Registration and coffee/snacks
12:30 - 1:00 PM	Registration and coffee/snacks
12:30 - 1:00 PM	Registration and coffee/snacks

And our sponsors

No items found.

Pricing

The symposium has a £20 registration fee per person, which helps us create a fantastic experience for everyone. Please make your registration deposit through the University of Sheffield (UofS) store link received in your confirmation e-mail. Once we’ve received your application, we will review it and send you a registration confirmation. If, for any reason, we’re unable to offer you a place, you’ll be notified and fully refunded.

What’s SMBio?

The SMBio single-molecule biology symposium is a 2-day event, bringing together scientists interested in single-molecule approaches to biology from all over the world to share their research, connect, and exchange ideas and experiences.

Previous Symposia

Take a look at our previous editions to get an impression of what it's like to attend!

SMBio 2025 West

Symposium

June 30, 2025

01-01-20

This is some text inside of a div block.

author empty

application empty

Start - end date

SMBio 2025 Nordics

Symposium

June 6, 2025

01-01-20

This is some text inside of a div block.

author empty

application empty

Start - end date

SMBio 2025 China

Symposium

June 4, 2025

01-01-20

This is some text inside of a div block.

author empty

application empty

Start - end date

SMBio 2025 UK & Ireland

Symposium

April 18, 2025

01-01-20

This is some text inside of a div block.

author empty

application empty

Start - end date

SMBio New York 2024

Symposium

June 17, 2025

01-01-20

This is some text inside of a div block.

author empty

application empty

Start - end date

SMBio 2024 London

Symposium

November 12, 2025

01-01-20

This is some text inside of a div block.

author empty

application empty

Start - end date

SMBio New York 2022

Symposium

June 17, 2025

01-01-20

This is some text inside of a div block.

author empty

application empty

Start - end date

Connect with us

Stop by at a conference or user event, or tune in for a live webinar!

View all

Button Text

SMBio 2026 Sheffield

Symposium

May 20, 2026

01-01-20

This is some text inside of a div block.

author empty

application empty

region empty

May 20, 2026

time empty

Sheffield, UK

No items found.

Immuno-oncology

Technology hub

Cell Avidity

Applications

Cell Therapy

Cell Engagers

Antibody Therapy

Solutions

Avidion

z-Movi

Avidigo services

Resources

Knowledge library

Publications

Exclusives

Avidion Early Access

Molecular biology

Technology hub

Dynamic Single-Molecule

Applications

DNA-Binding proteins

Protein Folding

Phase Separation

Mechanobiology

Cytoskeletal Structure and Transport

Solutions

C-Trap

Consumables & reagents

Resources

Knowledge library

Publications

LUMICKS University

Company

About us

Life at LUMICKS

Careers

News & events

News & Press

Events

Contact

info@lumicks.com