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Symposium

SMBio 2025 West

Single molecules. Joint research.

Start - end date

California, United States

The Quad Conference Center, 2400 Sand Hill Road, Menlo Park, CA 94025

Welcome to a new Symposium

We're excited to welcome you to the SMBio 2025 West, aimed at bringing together the single-molecule community and current and future C-trap users for two days of engaging discussions and networking.

Organized by

LUMICKS

See more. Know more.

LUMICKS

Shannon Yan, PhD

Assistant Professor

Stanford University

Keynote speakers

Steven Block, PhD

Professor of Applied Physics and Biology , Emeritus

Stanford University

Patrick Sung, PhD

Professor of Biochemistry and Structural Biology

UT Health San Antonio

Geeta Narlikar, PhD

Professor of Biochemistry and Biophysics

University of California

Carlos Bustamante, PhD

Professor

UC Berkeley

Preliminary agenda

|Day 1 | | | | | ------- | ------------------------------ | ------------------------------- | ----------------------------------------------------------------------------------------------------- | | **Time** | **Speaker** | **Affiliation** | **Talk Title** | | 8:00 AM | Registration and welcome | | | | 9:00 AM | Kickoff and Introduction | | | | 9:20 AM | Patrick Sung (Keynote Speaker) | UT Health San Antonio | TBD | | 10:10 AM | Shixin Liu | The Rockefeller University | Single-molecule studies of eukaryotic replication and transcription | | 10:35 AM | Nils Walter | University of Michigan | Life in Flux: Dynamic RNA:Protein Granule Assembly Shapes Biomolecular and Cellular Function | | 11:00 AM | Break | | | | 11:15 AM | Linda Bloom | University of Florida | Escherichia coli YoaA-chi and DinG helicases push and pull single-stranded DNA binding protein on DNA | | 11:40 AM | Tae-Hee Lee | Pennsylvania State University | Investigating phase separation of nucleosome arrays with single-molecule methods | | 12:05 PM | Sneha Bhat | UC Merced | Single-molecule studies reveal DNA sensor IFI16β inhibits AIM2 inflammasome via DNA competition | | 12:20 PM | Lunch | | | | 1:20 PM | Thomas Perkins | NIST and University of Colorado | Stretching the ankle of human β cardiac myosin | | 1:45 PM | Christoph Schmidt | Duke University | TBD | | 2:10 PM | Richard McKenney | UC Davis | Single Molecule Studies of Tau Oligomerization on Microtubules | | 2:35 PM | Break | | | | 2:45 PM | Poster Flash Talks | | | | 3:30 PM | Poster Session | | | | 5:00 PM | Steven Block (Keynote Speaker) | Stanford University | TBD | | 5:45 PM | Shannon Yan | Stanford University | TBD | | 6:15 PM | Break and Depart for Social | | | | 6:45 PM | Dinner and social | | |

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| Day 2 | | | | | -------- | ----------------------------------- | ---------------------------------------- | --------------------------------------------------------------------------------------------------------------------- | | **Time** | **Speaker** | **Affiliation** | **Talk Title** | | 8:00 AM | Welcome & Coffee | | | | 9:00 AM | Kickoff and Introduction to Day 2 | | | | 9:10 AM | Carlos Bustamante (Keynote Speaker) | UC Berkeley | TBD | | 9:55 AM | Jing Xu | UC Merced | Microtubules under force: dynamic stress reduction without softening | | 10:20 AM | Ben Van Houten | University of Pittsburgh | Single molecule analysis of PARP1 binding to nicks and nucleosomes: probing Allostery through inhibitors | | 10:45 AM | Poster Session | | | | 11:45 AM | Lunch | | | | 12:35 PM | Group Photo | | | | 12:45 PM | Yale Goldman | UC Davis | Native and HCM Mutant Cardiac Myosins in the Ultra-Fast Optical Trap | | 1:10 PM | Micah McCauley | Northeastern University | Histone acylation by cellular metabolites differentially regulates nucleosome array stability, dynamics, and mobility | | 1:35 PM | Brett O'Brien | Johns Hopkins University | Disentangling the physical basis of RNA toxicity in HD with optical tweezers | | 1:50 PM | Break | | | | 2:05 PM | Yann Chemla | University of Illinois, Urbana-Champaign | Measurement of bacteriophage infection kinetics in optically trapped, motile E. coli cells | | 2:30 PM | Hays Rye | Texas A&M University | Connecting catalyzed protein folding and allostery: the disordered tails of the GroEL chaperonin | | 2:55 PM | Longfu Xu | UC Berkeley | Single-Molecule Dissection of DNA Processing Machinery: Polymerase Exchange Dynamics and Conformational Force Generation in Viral Packaging Motor | | 3:10 PM | Break | | | | 3:20 PM | Geeta Narlikar (Keynote Speaker) | UCSF | TBD | | 4:05 PM | Gheorghe Chistol | Stanford University | TBD | | 4:30 PM | Yuri Lyubchenko | University of Nebraska Medical Center | TBD | | 5:00 PM | Closing Remarks and Poster Award | |

Day 1, Monday 17 March
12:30 - 1:00 PM	Registration and coffee/snacks
12:30 - 1:00 PM	Registration and coffee/snacks
12:30 - 1:00 PM	Registration and coffee/snacks

Day 1, Monday 17 March
12:30 - 1:00 PM	Registration and coffee/snacks
12:30 - 1:00 PM	Registration and coffee/snacks
12:30 - 1:00 PM	Registration and coffee/snacks

Day 1, Monday 17 March
12:30 - 1:00 PM	Registration and coffee/snacks
12:30 - 1:00 PM	Registration and coffee/snacks
12:30 - 1:00 PM	Registration and coffee/snacks

Brought to you by

And our sponsors

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Pricing

This Symposium requires a registration fee to help make it a fantastic event for everyone. To accommodate a broad variety of people, the pricing model is as follows:

PhD student or Postdoc: $75
PI or Industry: $200

The fee allows us to sustainably organize a recurring, high-quality meeting for the single-molecule community and covers breakfast, lunch and costs for the social networking evening for both days. After your registration is confirmed, we will be in touch to provide you with instructions on payment options.

What’s SMBio?

The SMBio single-molecule biology symposium is a 2-day event, bringing together scientists interested in single-molecule approaches to biology from all over the world to share their research, connect, and exchange ideas and experiences.

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Stop by at a conference or user event, or tune in for a live webinar!

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