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Symposium

SMBio 2024 London

Single molecules. Joint research.

Start - end date

London

MRC Laboratory of Medical Sciences

Welcome to a new Symposium

LUMICKS proudly presents the very first UK-wide symposium focusing on single-molecule research!

Organized by

David Rueda, PhD

Professor and Chair

Imperial College London

Mina Brett-Pitt, PhD

Senior Sales Manager

LUMICKS

Keynote speakers

Nynke Dekker, PhD

Statutory Professor of Biophysics

University of Oxford

Simon Boulton, PhD

Principal Group Leader

The Francis Crick Institute

Preliminary agenda

| Day 1 | | | | | ------- | ------------------------------ | ------------------------------- | ---------------------------------------------------------------------------------------------------- | | **Time** | **Speaker** | **Affiliation** | **Talk Title** | | 12:30 | Registration and coffee | | | | 13:00 | Welcome & Introduction by David Rueda | | | | | **Session 1: Genome organisation – Chair: Luis Aragon (MRC LMS)** || | | | 13:05 | Nynke Dekker (Keynote) | Oxford University | Adventures in DNA and chromatin replication using single-molecule biophysics | | 13:45 | Dominika Gruszka | Oxford University | Single-molecule imaging of nucleosome dynamics during DNA replication | | 14:05 | Paul Girvan | Imperial College London | Nucleosome flipping drives kinetic proof reading and processivity of histone exchange by SWR1 complex| | 14:25 | George Pobegalov | The Francis Crick Institute | Single-molecule insight into DNA loop extrusion by yeast cohesion | | 14:45 | Coffee Break | | | | | **Session 2: DNA Processing Enzymes – Chair: Christian Speck (MRC LMS)** || | | | 15:15 | Achillefs Kapanidis | Oxford University | Library-based single-molecule imaging for global analysis of protein-DNA interactions | | 15:45 | Graeme King | University College London | Probing the structure and interactions of negatively supercoiled DNA using optical tweezers and fluorescence imaging | | 16:05 | Andrea Candelli | LUMICKS | Single-Molecule Biology Revealing the molecular mechanisms of health and disease | | 16:25 | Closing remarks / Flash poster presentation by Mina Brett-Pitt | | | | 17:00 | Poster, Drinks and Dinner Reception | | |

| Day 2 | | | | | ------- | ------------------------------ | ------------------------------- | ----------------------------------------------------------------------------------------------------- | | **Time** | **Speaker** | **Affiliation** | **Talk Title** | | 09:00 | Simon Boulton (Keynote) | The Francis Crick Institute | Visualising homologous recombination | | | **Session 3: DNA Repair – Chair: Hasan Yardimci (The Francis Crick Institute)** | | | | 09:40 | Antony Oliver | University of Sussex | Live-cell single-molecule tracking of the Smc5/6 complex | | 10:00 | Lori Passmore | MRC LMB | Insights into how the FANCD2-FANCI DNA repair clamp interacts with DNA | | 10:20 | Neil Kad | University of Kent | Mechanism, manipulation and inhibition of DNA repair in bacteria | | 10:40 | Coffee Break | | | | | **Session 4: Biophysics Single Molecule Applications Across Scales – Chair: Sergi Garcia (KCL)** | | | | 11:10 | Anne Straube | Warwick University | Co-dependence of opposite polarity microtubule motors | | 11:30 | Alice Pyne | Sheffield University | Single molecule insights into how DNA supercoiling affects its interactions | | 11:50 | Vladimir Volkov | QMUL | Single-molecule approaches to studying force coupling between kinetochores and microtubule ends | | 12:10 | Sebastian Guettler | ICR | Wnt/beta-catenin signalling: molecular mechanisms and regulation by ADP-ribosylation |

Day 1, Monday 17 March
12:30 - 1:00 PM	Registration and coffee/snacks
12:30 - 1:00 PM	Registration and coffee/snacks
12:30 - 1:00 PM	Registration and coffee/snacks

Day 1, Monday 17 March
12:30 - 1:00 PM	Registration and coffee/snacks
12:30 - 1:00 PM	Registration and coffee/snacks
12:30 - 1:00 PM	Registration and coffee/snacks

Day 1, Monday 17 March
12:30 - 1:00 PM	Registration and coffee/snacks
12:30 - 1:00 PM	Registration and coffee/snacks
12:30 - 1:00 PM	Registration and coffee/snacks

Brought to you by

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Pricing

What’s SMBio?

The SMBio single-molecule biology symposium is a 2-day event, bringing together scientists interested in single-molecule approaches to biology from all over the world to share their research, connect, and exchange ideas and experiences.

Previous Symposia

Take a look at our previous editions to get an impression of what it's like to attend!

SMBio 2025 West

Symposium

June 30, 2025

01-01-20

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California, United States

SMBio 2025 Nordics

Symposium

June 6, 2025

01-01-20

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Copenhagen, Denmark

SMBio 2025 China

Symposium

June 4, 2025

01-01-20

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Heifei, China

SMBio 2025 UK & Ireland

Symposium

April 18, 2025

01-01-20

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Oxford, United Kingdom

SMBio New York 2024

Symposium

June 17, 2025

01-01-20

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New York, United States

SMBio 2024 London

Symposium

November 12, 2025

01-01-20

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London

SMBio New York 2022

Symposium

June 17, 2025

01-01-20

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New York, United States

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