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Symposium

SMBio 2024 London

Single molecules. Joint research.

Start - end date

London

MRC Laboratory of Medical Sciences

Welcome to a new Symposium

LUMICKS proudly presents the very first UK-wide symposium focusing on single-molecule research!

Organized by

David Rueda, PhD

Professor and Chair

Imperial College London

Mina Brett-Pitt, PhD

Senior Sales Manager

LUMICKS

Brought to you by

Keynote speakers

Nynke Dekker, PhD

Statutory Professor of Biophysics

University of Oxford

Simon Boulton, PhD

Principal Group Leader

The Francis Crick Institute

Preliminary agenda

| Day 1 | | | | | ------- | ------------------------------ | ------------------------------- | ---------------------------------------------------------------------------------------------------- | | **Time** | **Speaker** | **Affiliation** | **Talk Title** | | 12:30 | Registration and coffee | | | | 13:00 | Welcome & Introduction by David Rueda | | | | | **Session 1: Genome organisation – Chair: Luis Aragon (MRC LMS)** || | | | 13:05 | Nynke Dekker (Keynote) | Oxford University | Adventures in DNA and chromatin replication using single-molecule biophysics | | 13:45 | Dominika Gruszka | Oxford University | Single-molecule imaging of nucleosome dynamics during DNA replication | | 14:05 | Paul Girvan | Imperial College London | Nucleosome flipping drives kinetic proof reading and processivity of histone exchange by SWR1 complex| | 14:25 | George Pobegalov | The Francis Crick Institute | Single-molecule insight into DNA loop extrusion by yeast cohesion | | 14:45 | Coffee Break | | | | | **Session 2: DNA Processing Enzymes – Chair: Christian Speck (MRC LMS)** || | | | 15:15 | Achillefs Kapanidis | Oxford University | Library-based single-molecule imaging for global analysis of protein-DNA interactions | | 15:45 | Graeme King | University College London | Probing the structure and interactions of negatively supercoiled DNA using optical tweezers and fluorescence imaging | | 16:05 | Andrea Candelli | LUMICKS | Single-Molecule Biology Revealing the molecular mechanisms of health and disease | | 16:25 | Closing remarks / Flash poster presentation by Mina Brett-Pitt | | | | 17:00 | Poster, Drinks and Dinner Reception | | |

| Day 2 | | | | | ------- | ------------------------------ | ------------------------------- | ----------------------------------------------------------------------------------------------------- | | **Time** | **Speaker** | **Affiliation** | **Talk Title** | | 09:00 | Simon Boulton (Keynote) | The Francis Crick Institute | Visualising homologous recombination | | | **Session 3: DNA Repair – Chair: Hasan Yardimci (The Francis Crick Institute)** | | | | 09:40 | Antony Oliver | University of Sussex | Live-cell single-molecule tracking of the Smc5/6 complex | | 10:00 | Lori Passmore | MRC LMB | Insights into how the FANCD2-FANCI DNA repair clamp interacts with DNA | | 10:20 | Neil Kad | University of Kent | Mechanism, manipulation and inhibition of DNA repair in bacteria | | 10:40 | Coffee Break | | | | | **Session 4: Biophysics Single Molecule Applications Across Scales – Chair: Sergi Garcia (KCL)** | | | | 11:10 | Anne Straube | Warwick University | Co-dependence of opposite polarity microtubule motors | | 11:30 | Alice Pyne | Sheffield University | Single molecule insights into how DNA supercoiling affects its interactions | | 11:50 | Vladimir Volkov | QMUL | Single-molecule approaches to studying force coupling between kinetochores and microtubule ends | | 12:10 | Sebastian Guettler | ICR | Wnt/beta-catenin signalling: molecular mechanisms and regulation by ADP-ribosylation |

Day 1, Monday 17 March
12:30 - 1:00 PM	Registration and coffee/snacks
12:30 - 1:00 PM	Registration and coffee/snacks
12:30 - 1:00 PM	Registration and coffee/snacks

Day 1, Monday 17 March
12:30 - 1:00 PM	Registration and coffee/snacks
12:30 - 1:00 PM	Registration and coffee/snacks
12:30 - 1:00 PM	Registration and coffee/snacks

Day 1, Monday 17 March
12:30 - 1:00 PM	Registration and coffee/snacks
12:30 - 1:00 PM	Registration and coffee/snacks
12:30 - 1:00 PM	Registration and coffee/snacks

And our sponsors

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Pricing

What’s SMBio?

The SMBio single-molecule biology symposium is a 2-day event, bringing together scientists interested in single-molecule approaches to biology from all over the world to share their research, connect, and exchange ideas and experiences.

Previous Symposia

Take a look at our previous editions to get an impression of what it's like to attend!

SMBio 2025 West

Symposium

June 30, 2025

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SMBio 2025 Nordics

Symposium

June 6, 2025

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SMBio 2025 China

Symposium

June 4, 2025

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SMBio 2025 UK & Ireland

Symposium

April 18, 2025

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SMBio New York 2024

Symposium

June 17, 2025

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SMBio 2024 London

Symposium

November 12, 2025

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SMBio New York 2022

Symposium

June 17, 2025

01-01-20

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Connect with us

Stop by at a conference or user event, or tune in for a live webinar!

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SMBio 2026 Sheffield

Symposium

May 20, 2026

01-01-20

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May 20, 2026

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Sheffield, UK

Tuning CAR-T cells by targeting cancer-associated glycan in pancreatic cancer

Webinar

February 23, 2026

01-01-20

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Sangwoo (Steven) Park, PhD

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February 23, 2026

5:00 pm

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