Unraveling the Kinetics and Strength of T Cell Adhesion to Fibronecting using z-Movi®;

A new study in Cell Reports shows the first results obtained using z-Movi; ! Kamsma et al. used the z-Movi to measure the adhesion forces and kinetics of CD4⁺ T lymphocytes (CD4) to fibronectin in living conditions. They then investigated how these properties are influenced by interleukin-7 (IL-7), the main regulatory cytokine of CD4 cells. The results demonstrated that IL-7 accelerates CD4 adhesion but does not influence CD4 binding strength. Congratulations to all the authors!